The first mass extinction on earth occurred around 2.5 billion years ago, when a photosynthesizing bacterium appeared and released so much oxygen into the atmosphere that anaerobic life was largely wiped out. This is often called the Great Oxygenation Event, the Oxygen Catastrophe, or the Oxygen Holocaust. 

A 1959 Chicago Daily Tribune article about Robert Frost, who had recently proclaimed his confidence in humanity’s resilience in the face of missile threats, ran with the headline human race bomb proof, poet believes.

Arthur Schopenhauer referred to insurance as “a public sacrifice made on the altar of anxiety.”

The opening of a particle accelerator at Brookhaven National Laboratory in 2000 inspired fears that high-speed collisions might launch a chain reaction that could turn the earth into a hyperdense sphere about one hundred meters across. A risk calculation determined this to be unlikely; if the collider were to run for ten years, the chance was no greater than 1 in 50 million. “The word unlikely, however many times it is repeated,” wrote concerned scientists, “just isn’t enough to assuage our fears of this total disaster.”

According to sixth-century-bc Greek poet Hipponax of Colophon, in times of drought, famine, or plague an ugly or deformed person was chosen by the community to be pharmakós, or scapegoat. After being fed figs, barley cake, and cheese, he would be struck on the genitals with the bulbs and twigs of wild plants, led on a procession accompanied by flute, and burned on a pyre. His ashes were thrown into the sea. It is believed that Hipponax, whom Pliny the Elder once called “notoriously ugly,” may have been exaggerating the ritual.