Isolated from opium by the German chemist F. W. A. Sertürner around 1804, morphine (named after Morpheus, the Greek god of sleep and dreams) was used to treat opium addicts. Invented by Bayer Pharmaceuticals in 1898, heroin (derived from the Greek word for hero) was used to treat morphine addicts.

George Washington completed his second and final term as president in 1797 and moved back to Mount Vernon, where his farm manager, a Scotsman, convinced him to build a whiskey distillery to earn higher profits on his estate. “I make use of no barley in my distillery,” he wrote in 1798. “Rye chiefly and Indian corn in a certain proportion compose the materials from which the whiskey is made.” Having expanded operations by 1799, the year of his death, he owned five stills in a building of 2,250 square feet with a yearly yield of nearly 10,500 gallons. It is considered to have been one of the country’s largest distilleries at that time.