While on his American speaking tour in 1882, Oscar Wilde visited Leadville, Colorado, where he went into a saloon. There was a piano player in the corner with a sign over him that said: DON’T SHOOT THE PIANIST; HE’S DOING THE BEST HE CAN. It was, observed Wilde, “the only rational method of art criticism I have ever come across.” He also visited a nearby mine where, upon reaching the bottom, the miners implored him to stay for supper: “the first course being whiskey, the second whiskey, and the third whiskey.”

Overworked and suffering from chest and stomach conditions, Emperor Marcus Aurelius took a prescription from his physician, Galen, for opium. According to Galen, the emperor did not like that the drug made him drowsy, so he stopped taking it. Then he found himself unable to sleep, so he started taking it again.