Sent to suppress elements of Nathaniel Bacon’s Rebellion in 1676, British soldiers made a soup seasoned with Datura stramonium, a hallucinogen, “the effect of which,” as an eighteenth-century historian put it, “was a very pleasant comedy; for they turned natural fools upon it for several days; one would blow up a feather in the air, another would dart straws at it with much fury, and another, stark naked, was sitting up in a corner, like a monkey, grinning and making mows at them.” D. stramonium became known as jimson weed, named after Jamestown, Virginia, where the soldiers had been sent.

In the United States around 1787—the year that Thomas Jefferson took a three-month sabbatical to tour the vineyards of France and Italy—the average drinking American consumed the equivalent of an estimated six gallons of pure alcohol per year. The figure today is 2.2.

“Bomb the shit out of them!” was reportedly a drunken President Richard Nixon’s conclusion as to what should be done about Cambodia. Henry Kissinger recalled in an interview in 1999 that “two glasses of wine were quite enough to make him boisterous, just one more to grow bellicose or sentimental with slurred speech.”

In An Inquiry into the Effects of Ardent Spirits upon the Human Body and Mind, published in 1785, physician and Founding Father Benjamin Rush wrote that drunkenness, an “odious disease (for by that name it should be called),” appeared with, among other symptoms, “unusual garrulity…unusual silence…a disposition to quarrel…uncommon good humor and an insipid simpering or laugh…disclosure of their own or other people’s secrets…a rude disposition to tell those persons in company whom they know, their faults…certain extravagant acts which indicate a temporary fit of madness.”

About the presidential election of 1928, between anti-Prohibitionist Al Smith and Prohibitionist Herbert Hoover, H.L. Mencken wrote, “If Al wins tomorrow, it will be because the American people have decided at last to vote as they drink.” Hoover won, earning 444 of the 531 electoral-college votes.