“Utter damned rot!” is what William Berryman Scott, a former president of the American Philosophical Society, said in response to Alfred Wegener’s theory of continental drift, first proposed in 1912. “Wegener is not seeking the truth,” said a doubtful geologist, “he is advocating a cause and is blind to every argument and fact that tells against it.”

A scholar in Peking contracted malaria in 1899 and was given medication with an ingredient labeled “dragon bones.” The bone chips, he found, were inscribed with writing dating back to China’s second dynasty. Thousands more were uncovered in the decades following; many of these “oracle bones” had inscriptions recording celestial events, which scientists have since used to calculate changes in the length of an earth day and in the rate of the earth’s rotation.

In his autobiographical novel Boyhood, Leo Tolstoy describes his youthful joy in philosophical abstraction: “I frequently imagined myself a great man, who was discovering new truths for the good of mankind, and I looked on all other mortals with a proud consciousness of my dignity.” His euphoria didn’t last. “Strange to say,” he wrote, “whenever I came in contact with these mortals, I grew timid.” Soon he was “ashamed of every simplest word and motion.”

In 1965 Stanley Kubrick and Arthur C. Clarke discussed a film project, then called Journey Beyond the Stars. “Science-fiction films have always meant monsters or sex, so we have tried to find another term,” said Clarke. “The best we’ve been able to come up with is a space odyssey,” added Kubrick. “The far-flung islands Homer’s wonderful characters visited were no less remote to them than the planets our spacemen will soon be landing on are to us.”