| Drug | Synthesized by | Intended Use | Actual Use | Current Use | Criminalized in U.S. |
|---|---|---|---|---|---|
| Cocaine | Friedrich Gaedcke at a pharmacy in Domitz in 1855 | Local anesthetic, teeth whitener | Toothache drops, treatment for morphine addiction | Snorted, smoked, or injected as party drug | 1970 |
| Heroin | Felix Hoffman at Bayer in 1897 | Treatment for morphine addiction and tuberculosis | Cough suppressant, treatment for morphine addiction | Injected or smoked to induce euphoria and stupor | 1924 |
| Ecstasy (MDMA) | Anton Köllisch at Merck in 1912 | Treatment for abnormal bleeding | None | Ingested in pill form as rave drug | 1985 |
| LSD | Albert Hoffman at Sandoz Laboratories in 1938 | Respiratory and circulatory stimulant | Alcoholism, psychiatric panacea, CIA truth serum | Ingested to induce hallucinations | 1966 |
